This list includes 30 Diseases that start with I, from “Ichthyosis vulgaris” to “Ischemic stroke”. It is useful for quick reference, study, and initial clinical lookup. The list features genetic, infectious, vascular and inflammatory diseases commonly seen in practice.

Diseases that start with I are medical conditions whose standardized names begin with the letter I. Notable examples include “Ischemic stroke,” a major global cause of disability and death.

Below you’ll find the table with Disease, Symptoms, Causes and Treatments.

Disease: Contains the standardized disease name you can use for further lookup or citation.

Symptoms: Lists the 2–4 key symptoms to help you recognize common presentations quickly.

Causes: Summarizes the primary cause and main risk factors or pathophysiology in one concise line.

Treatments: Notes first-line or typical treatment options and when to seek specialist referral.

Diseases that start with I

NameICD-10/ICD-11 code(s)Key symptomsCauses & main treatments
InfluenzaJ09-J11fever, cough, sore throatinfluenza virus; antivirals, rest, fluids
Iron deficiency anemiaD50fatigue, pallor, shortness of breathlow iron (blood loss, poor diet); iron supplements, investigate cause
Ischemic heart diseaseI20-I25chest pain, shortness of breath, fatigueatherosclerosis; medications, PCI/CABG referral
Ischemic strokeI63sudden weakness, speech difficulty, vision lossblood vessel blockage; urgent thrombolysis, stroke unit care
ImpetigoL01honey-crust skin lesions, itching, rednessbacterial (Staph/Strep); topical/oral antibiotics
Infective endocarditisI33fever, new heart murmur, fatiguebacterial/fungal heart valve infection; IV antibiotics, cardiology care
Irritable bowel syndromeK58abdominal pain, bloating, diarrhea/constipationgut‑brain interaction, stress; diet, fiber, meds, CBT referral
Inflammatory bowel diseaseK50-K51abdominal pain, diarrhea, weight lossimmune-mediated gut inflammation; steroids, biologics, GI referral
Infectious mononucleosisB27fever, sore throat, swollen lymph nodesEpstein–Barr virus; rest, fluids, avoid contact sports
InsomniaG47.0difficulty falling asleep, daytime tirednessstress, mental/medical causes; sleep hygiene, CBT, short-term meds
IntussusceptionK56.1intermittent abdominal pain, vomiting, bloody stoolstelescoping of intestine (children); ultrasound reduction, surgery
Intestinal obstructionK56abdominal pain, vomiting, constipationadhesions, hernia, tumor; decompression, surgery
Inclusion body myositisslow muscle weakness, difficulty swallowing, fallsuncertain immune/degenerative; supportive care, neurology referral
Infantile spasmssudden spasms, developmental regression, seizuresoften structural/genetic; urgent neurology, ACTH or vigabatrin
Infant botulismconstipation, poor feeding, weak cry, floppy babyClostridium botulinum toxin ingestion; hospital care, human immunoglobulin
Invasive candidiasisfever, organ dysfunction, sepsis signsCandida bloodstream infection; IV antifungals, hospital care
Ichthyosis vulgarisdry, scaly skin, itchinggenetic skin barrier abnormality; emollients, dermatology care
Inclusion conjunctivitisred eye, discharge, eyelid swellingChlamydia trachomatis infection; topical/oral antibiotics, ophthalmology
Inflammatory breast cancerbreast swelling, redness, rapid enlargementaggressive breast cancer subtype; oncology referral, chemo/surgery
Ischemic colitisK55abdominal pain, bloody diarrhea, tendernessreduced intestinal blood flow; supportive care, vascular/surgical referral
Immune thrombocytopeniaD69.3easy bruising, bleeding, low plateletsautoimmune platelet destruction; steroids, hematology referral, IVIG
Idiopathic pulmonary fibrosisJ84.1progressive breathlessness, dry cough, fatigueunknown; antifibrotics, pulmonology referral, oxygen
Ischemic optic neuropathyH47.0sudden painless vision loss, visual field defectvascular compromise to optic nerve; urgent ophthalmology, manage vascular risk
IritisH20eye pain, light sensitivity, blurred visionautoimmune or infection; steroid eye drops, ophthalmology
Idiopathic intracranial hypertensionG93.2headache, visual disturbances, papilledemaunknown (obesity risk); weight loss, acetazolamide, neurology
Iliotibial band syndromelateral knee pain, tenderness with activityoveruse (runners); physical therapy, activity modification
Infantile hemangiomared raised skin lesion, growth phase, involution laterbenign vascular tumor; observation, propranolol, dermatology
Inhalation anthraxA22fever, severe respiratory distress, mediastinal wideningBacillus anthracis inhalation; urgent antibiotics, antitoxin, critical care
Infective keratitiseye pain, redness, reduced visionbacterial/fungal viral infection; topical antimicrobials, ophthalmology
Inflammatory myopathyM33,M60muscle weakness, fatigue, elevated CKimmune-mediated muscle inflammation; steroids, immunosuppressants, rheumatology

Descriptions

Influenza
Seasonal viral respiratory infection causing fever, aches and cough. Affects all ages, usually self-limited but can cause severe illness in older adults and young children.
Iron deficiency anemia
Common anemia that causes tiredness and breathlessness; more frequent in women, children and people with chronic blood loss.
Ischemic heart disease
Reduced blood flow to the heart causing angina or heart attacks, common in middle-aged and older adults.
Ischemic stroke
Brain injury from blocked artery. Rapid treatment improves outcomes; often causes lasting disability.
Impetigo
Contagious superficial skin infection, especially in children, usually treated with antibiotics.
Infective endocarditis
Infection of heart valves requiring prolonged treatment; risk in people with valve disease or IV drug use.
Irritable bowel syndrome
Chronic functional gut disorder with variable bowel habits; symptoms may flare with stress or foods.
Inflammatory bowel disease
Includes Crohn’s disease and ulcerative colitis, chronic relapsing conditions causing intestinal inflammation.
Infectious mononucleosis
Viral illness common in teens and young adults causing prolonged fatigue and sore throat.
Insomnia
Persistent trouble sleeping that impairs daytime function; common and treatable with behavioral approaches.
Intussusception
Pediatric emergency causing bowel obstruction, most common in infants aged 6–36 months.
Intestinal obstruction
Blocked intestine needing urgent care; can be partial or complete and may require surgery.
Inclusion body myositis
Progressive inflammatory muscle disease of older adults causing gradual weakness and disability.
Infantile spasms
Severe early-life epilepsy syndrome requiring prompt treatment to reduce developmental harm.
Infant botulism
Rare infant illness causing muscle weakness; requires urgent supportive care.
Invasive candidiasis
Serious systemic yeast infection in hospitalized or immunocompromised patients.
Ichthyosis vulgaris
Common inherited skin condition causing dry, flaky skin from childhood onward.
Inclusion conjunctivitis
Conjunctivitis caused by chlamydia, more common in newborns and sexually active adults.
Inflammatory breast cancer
Rare, rapid-onset breast cancer presenting like infection, needs urgent cancer treatment.
Ischemic colitis
Colon injury from poor blood flow, often in older adults with vascular disease.
Immune thrombocytopenia
Autoimmune low platelet disorder causing bleeding risk, variable course from acute to chronic.
Idiopathic pulmonary fibrosis
Progressive scarring of lungs in older adults, leads to breathlessness and reduced quality of life.
Ischemic optic neuropathy
Sudden loss of vision from reduced blood flow to the optic nerve, often in older adults.
Iritis
Inflammation of the iris causing pain and photophobia; treatable but can recur.
Idiopathic intracranial hypertension
Raised brain pressure without tumor, causes headaches and vision changes, often in young obese women.
Iliotibial band syndrome
Common cause of outer knee pain from friction of the iliotibial band in athletes.
Infantile hemangioma
Common benign blood-vessel tumor in infants; many regress spontaneously or respond to treatment.
Inhalation anthrax
Rare but severe form of anthrax causing life-threatening respiratory illness after spore inhalation.
Infective keratitis
Corneal infection that can threaten sight; urgent eye care improves outcomes.
Inflammatory myopathy
Group of autoimmune muscle diseases causing progressive weakness and slowed physical function.
If you think there is a missing term, let us know using the contact form.