No Chinese words start with the letter U, and this list stays empty for a clear reason tied to how Chinese sounds get written in the Roman alphabet. Chinese does not use letters the way English does. Instead, most learners and dictionaries rely on pinyin, the official romanization system that turns Mandarin sounds into letters people around the world can read. Pinyin has strict rules about which letters can open a word, and U is not one of them on its own.
The absence comes down to a spelling rule built into pinyin itself. When a Mandarin syllable has the “oo” sound and no consonant in front of it, pinyin writers do not spell it with a bare U. They spell it with a W instead, so the sound becomes “wu,” not “u.” This is why words like wǔ (five) or wǒ (I, me) start with W even though the vowel sound is the same one a U would make. Pinyin applies this substitution consistently, which erases U as a possible starting letter for any standalone Chinese word.
A few near matches still exist for anyone curious about this sound. Words spelled with u right after the letters j, q, x, or y do appear in pinyin, such as ju (chrysanthemum, in júhuā) or yu (fish, in yú). In those cases, the u sits inside the word rather than at its very start, so it does not count as a word beginning with U. Anyone searching for Chinese words in this category will find more useful results by looking under W, since that letter holds the true home of the “oo” sound in written Mandarin.