Here you’ll find 26 Prefixes that start with O, organized from “ob-” to “oxy-“. These prefixes often come from Latin or Greek and help with word-building, vocabulary study, and reading technical terms. Entries prioritize common, high-utility prefixes first, then technical forms, and include origins plus clear examples.

Prefixes that start with O are short meaningful elements added to word stems to alter or refine their sense. Many derive from Latin and Greek, and “oxy-” appears in “oxygen”, named during 18th-century chemical discoveries.

Below you’ll find the table with Prefix, Origin, Meaning, Examples, and Notes.

Prefix: Shows the prefix itself so you can quickly identify its spelling and common forms for use.

Origin: Gives the linguistic source so you understand historical roots and related forms across languages.

Meaning: Provides a concise definition (three to seven words) so you grasp the prefix’s basic sense at a glance.

Examples: Lists two to four clear words using the prefix so you see real usage and learn word-building.

Notes: Includes brief usage tips, variations, and links so you can explore exceptions or technical meanings further.

Prefixes that start with O

PrefixOriginMeaningExample words
ob-Latin (ob)against; in the way; towardobject; obstruct; oppose; occur
octa-Greek (oktō) and Latin (octo)eightoctagon; octopus; October; octet
oculo-Latin (oculus)relating to the eyeoculist; oculomotor; binocular
odonto-Greek (odous, odontos)relating to teethodontology; orthodontist; periodontics
odyno-Greek (odynē)painodynophagia; odynometer
oeno-Greek (oinos)relating to wineoenology; oenophile; oenology
oiko-Greek (oikos)house; household; dwellingecology; economy; ecumenical
oleo-Latin (oleum)relating to oiloleograph; oleoresin; oleomargarine
oligo-Greek (oligos)few; little; smalloligarchy; oligopoly; oligocene
omni-Latin (omnis)all; every; everywhereomniscient; omnivore; omnipresent
onco-Greek (onkos)tumor; mass; bulkoncology; oncogene; oncovirus
onto-Greek (on, ontos)being; existenceontology; ontogeny; ontologic
onycho-Greek (onyx, onykhos)nail; clawonychomycosis; onychophagy
oo-Greek (ōion)egg; ovumoocyte; oogenesis; oology
oophoro-Greek (ōophoron)relating to the ovaryoophorectomy; oophoritis
ophthalmo-Greek (ophthalmos)relating to the eyeophthalmology; ophthalmologist; ophthalmoscope
opistho-Greek (opisthen)behind; at the back; backwardopisthobranch; opisthosoma
organo-Greek (organon)organ; organic chemical compoundorganometallic; organophosphate; organogenesis
ornitho-Greek (ornis, ornithos)relating to birdsornithology; ornithopter; ornithomancy
oro-Greek (oros)mountainorography; orogeny; orology
oro-Latin (os, oris)mouthorofacial; oronasal; oral
ortho-Greek (orthos)straight; correct; rightorthodox; orthodontist; orthopedic
osmo-Greek (osmē)odor; smellosmia; osmology
osteo-Greek (osteon)relating to bonesosteoporosis; osteopath; osteoarthritis
oto-Greek (ous, otos)relating to the earotology; otoscope; otitis
oxy-Greek (oxys)sharp; acid; pointed; keenoxygen; oxymoron; oxyacetylene

Descriptions

ob-
A versatile prefix indicating opposition or movement toward. It often changes form, becoming oc-, of-, or op- before certain consonants.
octa-
Used for the number eight. October was the eighth month in the original Roman calendar, which began in March.
oculo-
The Latin-derived prefix for “eye,” often used in general and anatomical terms. Compare with the Greek-derived ophthalmo-.
odonto-
The standard prefix for anything related to teeth, forming the basis of many dental and medical specializations.
odyno-
A medical prefix used to denote pain, particularly pain that occurs when swallowing (odynophagia).
oeno-
Used in words concerning wine and winemaking. An oenophile is a connoisseur or lover of wine. Also spelled eno-.
oiko-
Forms words related to the house or environment. ‘Economy’ originally meant household management, while ‘ecology’ is the study of the house of nature.
oleo-
Indicates a connection to oil. An oleograph is a print textured to look like an oil painting.
oligo-
Used in science and politics to describe a state of having “few” or “little” of something, like an oligarchy (rule by the few).
omni-
A popular and powerful prefix signifying “all.” An omnivore eats all things (both plants and animals), and an omniscient being knows all things.
onco-
A key prefix in medicine referring to tumors and cancer. Oncology is the branch of medicine that specializes in treating cancer.
onto-
A philosophical and scientific prefix dealing with the nature of being or existence. Ontology is a major branch of metaphysics.
onycho-
A medical prefix for conditions related to the fingernails or toenails, such as onychomycosis (a fungal nail infection).
oo-
A biological prefix used for words related to eggs or ova. An oocyte is an immature egg cell in an ovary.
oophoro-
A specific medical prefix for the ovary, literally meaning “egg-bearing.” An oophorectomy is the surgical removal of an ovary.
ophthalmo-
The primary prefix for the eye in medical and scientific terminology. Compare with the more general Latin-derived oculo-.
opistho-
An anatomical prefix indicating a position at the back or rear of a body part.
organo-
Used in biology for organs and in chemistry for compounds containing carbon, especially when bonded to metal (organometallic).
ornitho-
The definitive prefix for all things related to birds. Ornithology is the scientific study of birds.
oro-
Used in geology and geography for terms related to mountains. Orogeny refers to the process of mountain formation.
oro-
An anatomical prefix for the mouth. It is distinct from the Greek prefix oro- meaning “mountain.”
ortho-
A very common prefix used to mean correct, straight, or upright, from religious belief (orthodox) to teeth straightening (orthodontics).
osmo-
Refers to the sense of smell. This is less common than the other osmo- related to pressure, which comes from a different root.
osteo-
The fundamental medical prefix for bones. Osteoporosis is a well-known condition where bones become weak and brittle.
oto-
The standard medical and scientific prefix for the ear. An otoscope is the instrument a doctor uses to look inside your ear.
oxy-
Has two main senses: “sharp” as in oxymoron (“sharp-dull”) and “acid” or “containing oxygen” as in oxygen (“acid-former”).
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