This list includes 32 Pills that start with Z, from “Zaleplon” to “Zytiga”. These entries mix brand and generic oral medications used for sleep, allergies, mood, cancer, and other common conditions worldwide.
[Pills that start with Z] are oral brand and generic medicines whose names begin with Z, spanning many therapeutic areas. Notable examples like Zaleplon and Zytiga show the range from sleep aids to cancer therapies.
Below you’ll find the table with Name, Generic name, Primary use, Drug class, Common side effects, and Notes.
Name: The pill’s marketed name, often the one you see on labels and prescriptions, so you can quickly identify it.
Generic name: The active compound name you may see on packaging or databases, useful when comparing alternatives or generics.
Primary use: How the medicine is most commonly used, summarized so you understand its main clinical purpose quickly.
Drug class: The therapeutic group the medicine belongs to, helping you know related drugs and expected effects at a glance.
Common side effects: Three to six typical adverse effects reported for the pill, so you can anticipate and discuss them with your provider.
Notes: Extra details such as typical strengths, notable prescribing cautions, or links to official product information for your reference.
Pills that start with Z
| Name | Type | Primary use | Therapeutic class |
|---|---|---|---|
| Zaleplon | Generic | Treats insomnia/trouble falling asleep | Sedative-hypnotic |
| Zanaflex | Brand | Relieves muscle spasms and tightness | Muscle relaxant |
| Zantac 360 | Brand | Prevents and relieves heartburn | H2 blocker |
| Zarontin | Brand | Controls absence seizures (petit mal) | Anticonvulsant |
| Zaroxolyn | Brand | Treats high blood pressure and fluid retention | Thiazide-like diuretic (water pill) |
| Zejula | Brand | Treats certain types of ovarian cancer | PARP inhibitor (cancer therapy) |
| Zelboraf | Brand | Treats melanoma with a specific gene mutation | BRAF inhibitor (cancer therapy) |
| Zemplar | Brand | Treats hyperparathyroidism in kidney disease | Vitamin D analog |
| Zepatier | Brand | Treats chronic Hepatitis C infection | Antiviral combination |
| Zestoretic | Brand | Treats high blood pressure | ACE inhibitor and diuretic combination |
| Zestril | Brand | Treats high blood pressure and heart failure | ACE inhibitor |
| Zetia | Brand | Lowers high cholesterol levels | Cholesterol absorption inhibitor |
| Ziac | Brand | Treats high blood pressure | Beta-blocker and diuretic combination |
| Zithromax | Brand | Treats a wide range of bacterial infections | Macrolide antibiotic |
| Ziprasidone | Generic | Treats schizophrenia and bipolar disorder | Atypical antipsychotic |
| Zocor | Brand | Lowers high cholesterol and triglyceride levels | Statin |
| Zohydro ER | Brand | Manages severe, long-term pain | Opioid analgesic (extended-release) |
| Zoloft | Brand | Treats depression, anxiety, OCD, and PTSD | Selective Serotonin Reuptake Inhibitor (SSRI) |
| Zolpidem | Generic | Treats insomnia/trouble falling asleep | Sedative-hypnotic |
| Zonegran | Brand | Treats partial seizures in adults with epilepsy | Anticonvulsant |
| Zonisamide | Generic | Treats partial seizures in adults with epilepsy | Anticonvulsant |
| Zortress | Brand | Prevents organ rejection after a kidney transplant | mTOR inhibitor immunosuppressant |
| Zovia | Brand | Prevents pregnancy | Combination oral contraceptive (birth control) |
| Zovirax | Brand | Treats herpes virus infections | Antiviral |
| Zubsolv | Brand | Treats opioid use disorder | Opioid partial agonist/antagonist |
| Zydelig | Brand | Treats certain types of blood cancer | PI3K delta inhibitor (cancer therapy) |
| Zykadia | Brand | Treats a specific type of non-small cell lung cancer | ALK inhibitor (cancer therapy) |
| Zyloprim | Brand | Prevents gout attacks and kidney stones | Xanthine oxidase inhibitor |
| Zyprexa | Brand | Treats schizophrenia and bipolar disorder | Atypical antipsychotic |
| Zyrtec | Brand | Relieves allergy and hay fever symptoms | Antihistamine |
| Zytiga | Brand | Treats advanced prostate cancer | Androgen biosynthesis inhibitor |
| Zurzuvae | Brand | Treats postpartum depression (PPD) | Neuroactive steroid (GABA-A receptor modulator) |
Descriptions
Zaleplon
A sedative-hypnotic used for the short-term treatment of insomnia. Common side effects include dizziness, drowsiness, lightheadedness, and problems with coordination.
Zanaflex
A muscle relaxant used to treat spasticity from conditions like MS or spinal cord injury. Side effects can include drowsiness, dizziness, dry mouth, and fatigue.
Zantac 360
An over-the-counter H2 blocker that reduces stomach acid to treat heartburn and acid indigestion. Side effects are rare but may include headache, dizziness, or constipation.
Zarontin
An anticonvulsant medication specifically used to control absence (petit mal) seizures in epilepsy. Common effects include nausea, stomach upset, drowsiness, and loss of appetite.
Zaroxolyn
A potent diuretic (water pill) used for high blood pressure and fluid retention (edema). Can cause dizziness, dehydration, low potassium, and increased blood sugar.
Zejula
An oral cancer medication known as a PARP inhibitor for certain types of advanced ovarian cancer. May cause nausea, fatigue, anemia, constipation, and vomiting.
Zelboraf
A targeted cancer therapy used to treat melanoma with a specific gene mutation (BRAF V600E). Side effects include rash, joint pain, hair loss, and sensitivity to sun.
Zemplar
An oral Vitamin D analog used to treat high parathyroid hormone levels in chronic kidney disease. Can cause high calcium levels, nausea, vomiting, and headache.
Zepatier
A combination antiviral drug used to cure chronic Hepatitis C infection (genotypes 1 or 4). Common side effects are usually mild and include fatigue, headache, and nausea.
Zestoretic
A combination pill with an ACE inhibitor and a diuretic for treating high blood pressure. May cause dizziness, a dry cough, fatigue, and lightheadedness.
Zestril
A very common ACE inhibitor used for high blood pressure, heart failure, and improving survival after a heart attack. Common side effects include a dry cough, dizziness, and headache.
Zetia
Works to lower high cholesterol by reducing its absorption from food. It is often used with a statin. Can cause diarrhea, joint pain, sinus inflammation, and fatigue.
Ziac
A combination pill with a beta-blocker and a diuretic used to treat high blood pressure. May cause dizziness, fatigue, slow heart rate, and nausea.
Zithromax
A popular antibiotic, often prescribed as a “Z-Pak,” to treat bacterial infections like pneumonia and sinusitis. Side effects can include diarrhea, nausea, and stomach pain.
Ziprasidone
An atypical antipsychotic for schizophrenia and bipolar disorder. It must be taken with food. Common side effects include drowsiness, dizziness, nausea, and restlessness.
Zocor
A widely used statin medication to lower “bad” cholesterol (LDL) and reduce heart attack risk. Side effects may include headache, muscle pain, and stomach upset.
Zohydro ER
An extended-release opioid for severe, around-the-clock pain when other treatments are inadequate. High-risk for addiction, can cause constipation, nausea, drowsiness, and dizziness.
Zoloft
A popular SSRI antidepressant used for depression, anxiety disorders, OCD, and PTSD. Side effects can include nausea, insomnia, dizziness, dry mouth, and sexual dysfunction.
Zolpidem
A widely prescribed sedative-hypnotic (brand name Ambien) for short-term treatment of insomnia. Side effects include next-day drowsiness, dizziness, and unusual dreams.
Zonegran
The brand name for zonisamide, an anticonvulsant used to help control partial seizures in epilepsy. Common side effects include drowsiness, dizziness, confusion, and loss of appetite.
Zonisamide
An anticonvulsant medication used with other drugs to treat partial seizures in adults with epilepsy. Can cause drowsiness, dizziness, loss of appetite, and confusion.
Zortress
An immunosuppressant used to prevent organ rejection in adult kidney or liver transplant patients. May cause swelling, high cholesterol, constipation, nausea, and diarrhea.
Zovia
A combination oral contraceptive (birth control pill) containing estrogen and progestin to prevent pregnancy. Side effects can include nausea, breast tenderness, headache, and mood changes.
Zovirax
An antiviral medication used to treat infections caused by the herpes virus, like cold sores, genital herpes, and shingles. Common side effects include nausea, headache, and diarrhea.
Zubsolv
A sublingual (under the tongue) tablet for opioid dependence treatment, containing buprenorphine and naloxone. Can cause headache, nausea, constipation, and withdrawal symptoms.
Zydelig
A targeted cancer therapy used for chronic lymphocytic leukemia (CLL) and certain lymphomas. May cause severe diarrhea, fever, fatigue, nausea, cough, and rash.
Zykadia
A targeted cancer therapy for non-small cell lung cancer with a specific genetic mutation (ALK-positive). Side effects include diarrhea, nausea, vomiting, fatigue, and liver problems.
Zyloprim
Used to prevent painful gout attacks and certain types of kidney stones by lowering uric acid levels in the body. May cause a rash, nausea, or stomach upset.
Zyprexa
An atypical antipsychotic used for schizophrenia and bipolar disorder. Known for causing significant weight gain, drowsiness, dizziness, increased appetite, and dry mouth.
Zyrtec
A very common over-the-counter antihistamine that provides 24-hour relief from allergy symptoms like sneezing and itching. It is known for being less drowsy than older antihistamines.
Zytiga
An oral medication for treating advanced prostate cancer. It works by blocking testosterone production. Side effects include fatigue, joint swelling, high blood pressure, and nausea.
Zurzuvae
A fast-acting, 14-day oral treatment for postpartum depression (PPD). Common side effects include drowsiness, dizziness, fatigue, common cold, and diarrhea.