This list includes 95 Medications that start with P, ranging from “Paclitaxel” to “Pyrimethamine”. Many are systemic prescription drugs used for infections, cancer, mental health, and chronic conditions.

Medications that start with P are generic drug names or active ingredients used worldwide. Notably, paclitaxel came from the Pacific yew and still anchors many cancer treatments.

Below you’ll find the table with Generic name, Drug class, Common uses, Common side effects, and Brand names.

Generic name: The official nonproprietary name so you can identify the active medication across brands and countries.

Drug class: Short label showing the medication’s pharmacologic family, helping you understand its general action and similar drugs.

Common uses: Typical conditions or purposes for prescription, so you can quickly see why a drug is prescribed.

Common side effects: Frequent or expected adverse effects listed to help you recognize and discuss likely reactions with providers.

Brand names: Well-known trade names help you match generic drugs to marketed products you may encounter.

Last updated: September 28, 2025.

Medical disclaimer: This list is informational and not medical advice; discuss medication decisions with a healthcare professional.

Medications that start with P

Drug NameBrand NamesDrug ClassCommon Uses
PaclitaxelTaxol, AbraxaneAntineoplastic agent (taxane)Cancer (breast, lung, ovarian)
PalbociclibIbranceAntineoplastic agent (CDK4/6 inhibitor)Breast cancer
PaliperidoneInvega, XeplionAtypical antipsychoticSchizophrenia, schizoaffective disorder
PalivizumabSynagisMonoclonal antibodyRSV infection prevention
PalonosetronAloxiAntiemetic (5-HT3 antagonist)Nausea and vomiting
PamidronateArediaBisphosphonateHigh blood calcium, bone metastases
PancrelipaseCreon, Zenpep, PancreazeDigestive enzymesPancreatic insufficiency
PancuroniumPavulonNeuromuscular-blocking agentAnesthesia, mechanical ventilation
PantoprazoleProtonix, Somac, PantolocProton pump inhibitor (PPI)GERD, heartburn, stomach ulcers
ParacetamolTylenol, Panadol, CalpolAnalgesic and antipyreticPain relief, fever reduction
ParicalcitolZemplarVitamin D analogSecondary hyperparathyroidism
ParoxetinePaxil, Seroxat, BrisdelleSSRI antidepressantDepression, anxiety, panic disorder
PasireotideSigniforSomatostatin analogCushing’s disease, acromegaly
PatiromerVeltassaPotassium binderHyperkalemia (high potassium)
PazopanibVotrientAntineoplastic agent (tyrosine kinase inhibitor)Kidney cancer, soft tissue sarcoma
PegfilgrastimNeulasta, FulphilaColony-stimulating factorNeutropenia prevention
PegloticaseKrystexxaUrate-lowering agent (enzyme)Chronic gout
PembrolizumabKeytrudaAntineoplastic agent (PD-1 inhibitor)Cancer (melanoma, lung, and others)
PemetrexedAlimtaAntineoplastic agent (antifolate)Lung cancer, mesothelioma
PenciclovirDenavirAntiviral agentCold sores (herpes labialis)
PenicillamineCuprimine, DepenChelating agentWilson’s disease, rheumatoid arthritis
Penicillin VPen-Vee K, VeetidsPenicillin antibioticBacterial infections
PentamidineNebuPent, PentamAntiprotozoal agentPneumocystis pneumonia (PCP)
PentazocineTalwinOpioid analgesicModerate to severe pain
PentobarbitalNembutalBarbiturateSeizures, sedation
Pentosan polysulfate sodiumElmironBladder protectantInterstitial cystitis (bladder pain)
PentoxifyllineTrentalHemorheologic agentIntermittent claudication
PerampanelFycompaAnticonvulsantSeizures
PerindoprilCoversyl, AceonACE inhibitorHypertension, heart failure
PermethrinNix, Elimite, ActicinScabicide, pediculicideScabies, lice
PerphenazineTrilafonTypical antipsychoticSchizophrenia, severe nausea
PertuzumabPerjetaAntineoplastic agent (monoclonal antibody)Breast cancer
PethidineDemerol, MeperidineOpioid analgesicModerate to severe pain
PhenelzineNardilMAOI antidepressantDepression, panic disorder
PhenobarbitalLuminal, SolfotonBarbiturate anticonvulsantSeizures
PhenoxybenzamineDibenzylineAlpha-blockerPheochromocytoma
PhentermineAdipex-P, LomairaAnorectic (appetite suppressant)Obesity
PhentolamineRegitine, OraVerseAlpha-blockerHypertensive crisis, extravasation
PhenylephrineNeo-Synephrine, Sudafed PEDecongestant (alpha-adrenergic agonist)Nasal congestion, low blood pressure
PhenytoinDilantin, EpanutinAnticonvulsantSeizures
PhytonadioneMephyton, Vitamin K1Vitamin/Clotting factor synthesis agentVitamin K deficiency, warfarin reversal
PilocarpineSalagen, Isopto CarpineCholinergic agonistDry mouth, glaucoma
PimecrolimusElidelTopical calcineurin inhibitorAtopic dermatitis (eczema)
PimozideOrapAntipsychoticTourette’s syndrome
PindololViskenBeta-blockerHypertension
PioglitazoneActosThiazolidinedione antidiabetic agentType 2 diabetes
PiperacillinPipracilPenicillin antibioticBacterial infections
PirfenidoneEsbriet, PirespaAntifibrotic agentIdiopathic pulmonary fibrosis (IPF)
PiroxicamFeldeneNonsteroidal anti-inflammatory drug (NSAID)Pain, inflammation, arthritis
PitavastatinLivalo, ZypitamagStatinHigh cholesterol
PitolisantWakixHistamine H3 receptor antagonist/inverse agonistNarcolepsy
PivmecillinamSelexidPenicillin antibioticUrinary tract infections (UTIs)
PlerixaforMozobilStem cell mobilizerStem cell transplant
PodofiloxCondyloxAntimitotic agentGenital warts
PomalidomidePomalyst, ImnovidImmunomodulatory agentMultiple myeloma
PonatinibIclusigAntineoplastic agent (tyrosine kinase inhibitor)Leukemia (CML, ALL)
PosaconazoleNoxafil, PosanolAzole antifungalFungal infections
Potassium chlorideK-Dur, Klor-Con, Slow-KElectrolyte supplementHypokalemia (low potassium)
Potassium citrateUrocit-KAlkalinizing agentKidney stones
PralatrexateFolotynAntineoplastic agent (antifolate)T-cell lymphoma
PralidoximeProtopam Chloride, 2-PAMCholinesterase reactivatorOrganophosphate poisoning antidote
PramipexoleMirapex, SifrolDopamine agonistParkinson’s disease, restless legs syndrome
PramlintideSymlinAmylin analogDiabetes (Type 1 and 2)
PrasugrelEffient, EfientAntiplatelet agentAcute coronary syndrome
PravastatinPravachol, LipostatStatinHigh cholesterol
PraziquantelBiltricideAnthelminticParasitic worm infections
PrazosinMinipressAlpha-blockerHypertension, PTSD nightmares
PrednisoloneOrapred, Prelone, PediapredCorticosteroidInflammation, allergies, autoimmune disease
PrednisoneDeltasone, RayosCorticosteroidInflammation, allergies, autoimmune disease
PregabalinLyrica, Alzain, LecaentAnticonvulsant, neuropathic pain agentNerve pain, fibromyalgia, seizures, anxiety
PretomanidPretomanidAntitubercular agentTuberculosis (TB)
PrilocaineCitanestLocal anestheticAnesthesia
PrimaquinePrimaquineAntimalarialMalaria
PrimidoneMysolineAnticonvulsantSeizures
ProbenecidProbalan, BenemidUricosuric agentGout, antibiotic booster
ProcarbazineMatulaneAntineoplastic agent (alkylating agent)Hodgkin’s lymphoma, brain tumors
ProchlorperazineCompazine, Compro, StemetilAntiemetic, typical antipsychoticSevere nausea and vomiting, anxiety, psychosis
ProcyclidineKemadrinAnticholinergic agentParkinsonism, drug-induced movement disorders
ProgesteronePrometrium, Crinone, EndometrinHormone (progestin)Hormone therapy, infertility
ProguanilPaludrineAntimalarialMalaria prevention
PromethazinePhenergan, PrometheganAntihistamine, antiemeticAllergies, motion sickness, nausea
PropafenoneRythmol, RytmonormAntiarrhythmicAtrial fibrillation
PropanthelinePro-BanthineAnticholinergic agentExcessive sweating, GI spasms, overactive bladder
ProparacaineAlcaine, OphthaineTopical anestheticOphthalmic procedures
PropofolDiprivanGeneral anestheticAnesthesia, sedation
PropranololInderal, InnoPran XLBeta-blockerHypertension, angina, anxiety, migraine
PropylthiouracilPropyl-Thyracil (PTU)Antithyroid agentHyperthyroidism
Protamine sulfateProtamineHeparin antidoteHeparin overdose
ProtriptylineVivactilTricyclic antidepressantDepression
PseudoephedrineSudafed, Contac, NexafedDecongestantNasal and sinus congestion
PsylliumMetamucil, Konsyl, FybogelBulk-forming laxativeConstipation, fiber supplement
Pyrantel pamoateReese’s Pinworm Medicine, Pin-XAnthelminticPinworm infections
PyrazinamidePyrazinamideAntitubercular agentTuberculosis (TB)
PyridostigmineMestinon, RegonolCholinesterase inhibitorMyasthenia gravis, nerve gas reversal
PyrimethamineDaraprimAntiparasitic agentToxoplasmosis, malaria

Descriptions

Paclitaxel
A chemotherapy drug that works by stopping cancer cells from dividing and growing. It is administered as an intravenous (IV) infusion in a hospital or clinic setting.
Palbociclib
A targeted therapy for certain types of advanced breast cancer. It works by blocking proteins that help cancer cells grow and divide. Taken as a daily oral capsule.
Paliperidone
Helps rebalance dopamine and serotonin to improve thinking, mood, and behavior. Available as an oral tablet or a long-acting injection for consistent medication levels.
Palivizumab
A man-made antibody given as a monthly injection during RSV season to protect high-risk infants and young children from severe respiratory syncytial virus (RSV) disease.
Palonosetron
A powerful anti-nausea medication used to prevent nausea and vomiting caused by chemotherapy or surgery. It works by blocking serotonin, a natural substance that can cause vomiting.
Pamidronate
Slows down bone breakdown. Used to treat high calcium levels caused by cancer and to manage bone damage from certain cancers like multiple myeloma or breast cancer.
Pancrelipase
A mixture of digestive enzymes (lipase, protease, amylase) used by people whose pancreas does not produce enough enzymes to digest food, such as in cystic fibrosis or chronic pancreatitis.
Pancuronium
A muscle relaxant used during surgery or to help a patient on a breathing machine (ventilator). It does not provide pain relief or sedation, so it’s used with other anesthetic drugs.
Pantoprazole
Reduces the amount of acid your stomach makes. Used to treat acid reflux, heal ulcers, and manage conditions involving excessive stomach acid. Available as prescription and OTC.
Paracetamol
A very common over-the-counter medicine for mild to moderate pain and fever. Also known as acetaminophen in the US. Overdose can cause severe liver damage.
Paricalcitol
A form of vitamin D used to treat or prevent overactive parathyroid glands in people with chronic kidney disease. It helps control parathyroid hormone, calcium, and phosphorus levels.
Paroxetine
An antidepressant that works by increasing levels of serotonin in the brain. It can also treat OCD and PTSD. Do not stop taking it suddenly to avoid withdrawal symptoms.
Pasireotide
Mimics a natural hormone to reduce the production of other hormones. Used to treat Cushing’s disease by lowering cortisol levels and acromegaly by lowering growth hormone levels.
Patiromer
A medication that binds to potassium in the gut, preventing it from being absorbed into the body. Used to treat high potassium levels, often seen in patients with kidney disease.
Pazopanib
A targeted cancer drug that blocks signals that cancer cells need to grow and survive. It is taken as a daily oral tablet.
Pegfilgrastim
A long-acting medication that stimulates the bone marrow to produce more white blood cells (neutrophils). It helps prevent infection in patients receiving chemotherapy.
Pegloticase
An enzyme given by IV infusion to break down uric acid in the blood. It is used for severe, treatment-resistant gout when other medications haven’t worked.
Pembrolizumab
An immunotherapy drug that helps your own immune system attack and kill cancer cells. It has been approved for a wide variety of different cancers.
Pemetrexed
A chemotherapy drug that interferes with the DNA of cancer cells, preventing them from growing and multiplying. It is given as an intravenous (IV) infusion.
Penciclovir
An antiviral cream applied directly to cold sores on the lips and face. It helps to speed up healing and reduce pain and itching by stopping the herpes virus from multiplying.
Penicillamine
Binds to excess copper in the body, allowing it to be removed through urine. It’s the primary treatment for Wilson’s disease and is also used for severe rheumatoid arthritis.
Penicillin V
An oral antibiotic used to treat a range of bacterial infections, such as strep throat, scarlet fever, and certain skin infections. It works by stopping bacteria from building their cell walls.
Pentamidine
An antimicrobial medication used to treat and prevent a serious lung infection called Pneumocystis pneumonia (PCP), which is common in people with weakened immune systems.
Pentazocine
An opioid pain reliever for moderate to severe pain. It is sometimes combined with naloxone to prevent misuse. Carries risks of addiction and respiratory depression like other opioids.
Pentobarbital
A barbiturate that slows down the activity of the brain and nervous system. It is used short-term to treat seizures or to cause sedation before surgery. Highly controlled substance.
Pentosan polysulfate sodium
Thought to work by creating a protective layer on the bladder wall, shielding it from irritating substances in the urine. It is the only oral drug specifically approved for bladder pain syndrome.
Pentoxifylline
Improves blood flow by making red blood cells more flexible and decreasing blood viscosity. This helps relieve leg pain caused by poor circulation (intermittent claudication).
Perampanel
An anti-seizure medication that works by reducing abnormal electrical activity in the brain. It is used with other medications to treat partial-onset and generalized tonic-clonic seizures.
Perindopril
Relaxes blood vessels, making it easier for the heart to pump blood. Used to treat high blood pressure and to prevent heart attacks in people with stable coronary artery disease.
Permethrin
A topical medication used to treat infestations of lice and scabies mites. It works by paralyzing and killing the insects and their eggs. Available over-the-counter and by prescription.
Perphenazine
An older antipsychotic used to manage symptoms of schizophrenia. It is also effective for controlling severe nausea and vomiting in adults. Can cause movement-related side effects.
Pertuzumab
A targeted therapy for HER2-positive breast cancer. It is used with other cancer drugs (trastuzumab and chemotherapy) to block signals that promote cancer cell growth.
Pethidine
A synthetic opioid used for short-term relief of moderate to severe pain, often during and after surgery. Its use has declined due to risks of toxicity, especially in older adults.
Phenelzine
A powerful antidepressant from the monoamine oxidase inhibitor (MAOI) class. It is typically reserved for severe depression that hasn’t responded to other treatments due to many food/drug interactions.
Phenobarbital
An older medication used to control various types of seizures. It works by slowing down brain activity. It is a controlled substance and can be habit-forming.
Phenoxybenzamine
An irreversible alpha-blocker used to manage blood pressure and sweating in patients with a rare adrenal gland tumor called pheochromocytoma, often before surgery.
Phentermine
A stimulant medication used short-term to decrease appetite as part of a weight loss plan that includes diet and exercise. It works on the central nervous system.
Phentolamine
Used to prevent or treat skin injury caused by the leakage of certain IV drugs (extravasation). It is also used to manage severe high blood pressure (hypertensive crisis).
Phenylephrine
A common over-the-counter decongestant that shrinks blood vessels in the nasal passages. Also used in hospitals as an injection to raise dangerously low blood pressure.
Phenytoin
A widely used medication for controlling and preventing tonic-clonic (grand mal) and partial seizures. It works by stabilizing the electrical activity in the brain. Requires blood level monitoring.
Phytonadione
This is Vitamin K1. It is used as a medicine to treat and prevent bleeding problems caused by vitamin K deficiency or to quickly reverse the effects of the blood thinner warfarin.
Pilocarpine
Increases saliva production to treat dry mouth caused by Sjögren’s syndrome or radiation therapy. As eye drops, it reduces pressure inside the eye to treat glaucoma.
Pimecrolimus
A non-steroid cream used to treat mild to moderate eczema. It works by calming the skin’s immune system to reduce inflammation, itching, and redness.
Pimozide
An antipsychotic medication specifically used to suppress the motor and phonic tics in patients with severe Tourette’s syndrome who have not responded to other treatments.
Pindolol
A beta-blocker used to treat high blood pressure. Unlike some other beta-blockers, it has ‘intrinsic sympathomimetic activity,’ meaning it can slightly stimulate beta receptors as well as block them.
Pioglitazone
Helps control blood sugar levels by making the body’s cells more sensitive to insulin. It is an oral medication for type 2 diabetes, used with diet and exercise.
Piperacillin
A powerful, broad-spectrum penicillin antibiotic used to treat serious bacterial infections, such as pneumonia and skin, gynecological, and abdominal infections. Often combined with tazobactam (Zosyn).
Pirfenidone
A medication used to treat a serious lung disease called idiopathic pulmonary fibrosis. It is thought to work by reducing fibrosis (scarring) and inflammation in the lungs.
Piroxicam
An NSAID used to relieve the pain, swelling, and stiffness of osteoarthritis and rheumatoid arthritis. It has a long duration of action, allowing for once-daily dosing.
Pitavastatin
A statin medication that lowers levels of ‘bad’ cholesterol (LDL) and triglycerides in the blood while raising ‘good’ cholesterol (HDL). Used to reduce cardiovascular risk.
Pitolisant
A unique medication for narcolepsy that works by increasing histamine levels in the brain to promote wakefulness. It helps reduce excessive daytime sleepiness and cataplexy.
Pivmecillinam
An antibiotic specifically effective against bacteria that cause urinary tract infections. It’s widely used in Europe for uncomplicated UTIs.
Plerixafor
A medication used to move hematopoietic stem cells from the bone marrow into the bloodstream so they can be collected for autologous transplant in patients with certain cancers.
Podofilox
A topical solution or gel applied directly to external genital and perianal warts. It works by stopping the growth of the wart tissue, causing it to die and fall off.
Pomalidomide
Related to thalidomide, this drug helps the immune system attack cancer cells and prevents their growth. It is used for multiple myeloma that has relapsed after other treatments.
Ponatinib
A potent targeted therapy for certain types of chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) that are resistant to other treatments.
Posaconazole
A broad-spectrum antifungal medication used to treat and prevent serious fungal infections, especially in people with weakened immune systems.
Potassium chloride
A mineral supplement used to treat or prevent low levels of potassium in the blood. It is essential for the proper functioning of the heart, muscles, and nerves.
Potassium citrate
Makes the urine less acidic, which helps prevent certain types of kidney stones (uric acid, calcium oxalate) from forming. Also used to correct certain metabolic problems.
Pralatrexate
A chemotherapy drug used to treat peripheral T-cell lymphoma that has returned or not responded to other treatments. It works by blocking an enzyme cancer cells need to grow.
Pralidoxime
An antidote used along with atropine to treat poisoning by certain pesticides (organophosphates) or chemical nerve agents. It works by reactivating an essential enzyme blocked by the poison.
Pramipexole
Mimics the action of dopamine in the brain. It is used to treat the symptoms of Parkinson’s disease and to manage moderate to severe restless legs syndrome (RLS).
Pramlintide
A man-made form of a hormone called amylin. It is injected at mealtimes to help control blood sugar levels in people with diabetes who use insulin but still have high post-meal sugars.
Prasugrel
A potent antiplatelet medication used with aspirin to prevent blood clots in people who have had a heart attack or certain heart procedures (like stenting).
Pravastatin
A statin medication used to lower high cholesterol and triglyceride levels. It helps reduce the risk of heart attack, stroke, and other heart complications.
Praziquantel
A medication used to treat infections caused by parasitic worms like schistosomes (blood flukes) and tapeworms. It works by paralyzing the worms so the body can remove them.
Prazosin
Relaxes blood vessels to lower blood pressure. While originally for hypertension, it is now more commonly used off-label to treat nightmares associated with post-traumatic stress disorder (PTSD).
Prednisolone
A steroid that prevents the release of substances in the body that cause inflammation. Used for a wide variety of conditions, including asthma, allergic reactions, and arthritis.
Prednisone
A very common oral corticosteroid that reduces inflammation and suppresses the immune system. It must be converted by the liver to its active form, prednisolone.
Pregabalin
Calms overactive nerves to treat nerve pain (from diabetes or shingles), fibromyalgia, and certain types of seizures. It is also used for generalized anxiety disorder. A controlled substance.
Pretomanid
Part of a three-drug combination regimen used to treat specific, highly drug-resistant forms of tuberculosis. It is a newer agent that helps shorten and simplify treatment.
Prilocaine
A local anesthetic similar to lidocaine. It is used to numb an area of the body to block pain during dental procedures or minor surgeries. Often combined with epinephrine.
Primaquine
An antimalarial drug primarily used to eradicate the dormant liver forms of the parasite that causes relapsing malaria (P. vivax and P. ovale).
Primidone
An older anticonvulsant medication used to control grand mal, psychomotor, and focal epileptic seizures. It is metabolized in the body to phenobarbital and another active compound.
Probenecid
Increases the excretion of uric acid in the urine, helping to prevent gout attacks. It is also used to boost the blood levels and effectiveness of certain antibiotics, like penicillin.
Procarbazine
A chemotherapy drug used as part of a combination regimen to treat Hodgkin’s lymphoma and certain brain cancers. It works by damaging the DNA of cancer cells.
Prochlorperazine
Primarily used to control severe nausea and vomiting. At higher doses, it can be used to treat psychosis or non-psychotic anxiety. It can cause drowsiness and movement side effects.
Procyclidine
An anticholinergic drug used to treat the stiffness, tremors, and spasms caused by Parkinson’s disease or as a side effect of certain antipsychotic medications.
Progesterone
A female hormone important for regulating the menstrual cycle and pregnancy. Used in hormone replacement therapy, to support pregnancy, and for menstrual disorders.
Proguanil
Used in combination with atovaquone (as Malarone) or chloroquine to prevent malaria. It works by stopping the malaria parasite from reproducing in the body.
Promethazine
A first-generation antihistamine with strong sedative and anti-nausea effects. Used for allergies, motion sickness, and post-operative nausea. Can cause significant drowsiness.
Propafenone
A medication used to treat certain types of irregular heartbeats, especially atrial fibrillation. It works by stabilizing the heart’s rhythm.
Propantheline
Reduces muscle spasms and secretions. It is used to treat stomach/intestinal spasms, overactive bladder, and sometimes to reduce excessive sweating (hyperhidrosis).
Proparacaine
A local anesthetic eye drop used to numb the surface of the eye for short medical procedures, such as measuring eye pressure or removing a foreign object.
Propofol
A powerful, short-acting intravenous medication used to start and maintain general anesthesia or to sedate patients in the ICU. It has a rapid onset and quick recovery time.
Propranolol
A non-selective beta-blocker used for many conditions, including high blood pressure, chest pain, irregular heartbeats, performance anxiety, and migraine prevention.
Propylthiouracil
A medication that treats an overactive thyroid (hyperthyroidism) by blocking the production of thyroid hormone. It is one of the main treatments for Graves’ disease.
Protamine sulfate
A medication used to rapidly reverse the anticoagulant effects of heparin. It is given intravenously when there is severe bleeding or a need to quickly neutralize heparin after surgery.
Protriptyline
A tricyclic antidepressant (TCA) that is more stimulating than others in its class. It is used to treat depression, particularly in patients who are withdrawn and lethargic.
Pseudoephedrine
A highly effective oral decongestant that shrinks swollen nasal passages to relieve sinus pressure and congestion. Its sale is restricted in many places as it can be used to make methamphetamine.
Psyllium
A soluble fiber derived from the husks of Plantago ovata seeds. It absorbs water in the gut to create a softer, bulkier stool that is easier to pass, relieving constipation.
Pyrantel pamoate
An over-the-counter medication used to treat intestinal worm infections, most commonly pinworms. It works by paralyzing the worms, which are then passed out of the body in the stool.
Pyrazinamide
A primary medication used in combination with other drugs to treat active tuberculosis. It is critical for shortening the duration of TB therapy. Can be toxic to the liver.
Pyridostigmine
Improves muscle strength in patients with myasthenia gravis by preventing the breakdown of acetylcholine, a chemical that nerves use to communicate with muscles.
Pyrimethamine
An antiparasitic drug used with a sulfonamide to treat toxoplasmosis, a serious infection common in immunocompromised individuals. Also used for certain types of malaria.
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