This list includes 13 Medications that start with U, from “ubrogepant” to “ustekinumab”. Many are small molecules and biologics used for pain relief, immune disorders, and infections.

Medications that start with U are prescription drugs whose generic names begin with the letter U. Notable examples include ustekinumab, a biologic that reshaped psoriasis care, and ubrogepant, an oral migraine treatment.

Below you’ll find the table with Generic name, Brand name, Drug class, Common uses, Common side effects, Typical dosage/formulation.

Generic name: Shows the official, nonproprietary drug name so you can identify the medication across brands and international sources.

Brand name: Lists common trade names so you recognize products you may see on prescriptions or packaging in your region.

Drug class: Identifies the therapeutic class to help you understand how the medicine works and its related alternatives.

Common uses: Summarizes typical conditions the drug treats so you know why a provider might prescribe it.

Common side effects: Lists frequent adverse effects to watch for and discuss with a clinician if they occur during treatment.

Typical dosage/formulation: Notes usual doses and available forms so you can match prescriptions and understand how the medicine is taken.

Medications that start with U

Generic NameBrand NamesDrug ClassTypical Adult Dose Range
ubrogepantUbrelvyCGRP receptor antagonist (gepant)50–100 mg as needed for migraine attack
upadacitinibRinvoqJanus kinase (JAK) inhibitor15–45 mg once daily
ulipristal acetateElla, FibristalSelective progesterone receptor modulator (SPRM)30 mg single dose (emergency contraception)
ustekinumabStelaraInterleukin-12 and -23 antagonist45 or 90 mg by injection every 8–12 weeks
ursodiolActigall, Urso, Urso ForteGallstone dissolution agent, bile acid8–10 mg/kg/day in 2–3 divided doses
umeclidiniumIncruse ElliptaLong-acting muscarinic antagonist (LAMA)62.5 mcg inhaled once daily
urokinaseKinlytic, AbbokinaseThrombolytic agentVaries by use (e.g., 5,000 IU for catheter clearance)
ureaUreacin, Keralac, UtopicKeratolytic10–40% cream/lotion applied 1–2 times daily
urofollitropinBravelle, FertinexGonadotropin (follicle-stimulating hormone)75–150 IU daily by injection
urapidilEbrantil, UrapreneAlpha-1 adrenergic blocker30–60 mg twice daily (oral)
udenafilZydenaPDE5 inhibitor100 mg as needed before sexual activity
unoprostoneResculaProstaglandin analog1 drop in affected eye(s) twice daily
ulinastatinMiraclid, UlinasProtease inhibitor50,000–100,000 IU by IV infusion

Descriptions

ubrogepant
An oral medication used for the immediate treatment of migraine headaches. It works by blocking a protein involved in migraine pain signals, providing relief from pain and other symptoms.
upadacitinib
An oral pill that treats various autoimmune conditions like rheumatoid arthritis, Crohn’s disease, and eczema. It works by calming an overactive immune system to reduce inflammation.
ulipristal acetate
Primarily used as an emergency contraceptive to prevent pregnancy after unprotected sex. It can also be prescribed in lower daily doses to treat uterine fibroids.
ustekinumab
A biologic medication given by injection to treat autoimmune diseases like psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis by targeting inflammatory proteins.
ursodiol
A naturally occurring bile acid used to dissolve certain types of gallstones and to treat a liver disease called primary biliary cholangitis (PBC).
umeclidinium
An inhaler used for long-term maintenance treatment of chronic obstructive pulmonary disease (COPD). It helps relax the muscles around the airways to make breathing easier.
urokinase
An enzyme medication, often called a “clot-buster,” used in hospitals to dissolve blood clots in the lungs (pulmonary embolism), deep veins, or to clear blocked IV catheters.
urea
A topical medication available in creams and lotions to treat very dry, rough skin conditions or to soften and remove damaged nails. It works by moisturizing and breaking down hard skin.
urofollitropin
An injectable hormone used in fertility treatments to help stimulate egg development in the ovaries of women who have difficulty ovulating.
urapidil
A medication used to treat high blood pressure (hypertension). It works by relaxing blood vessels, which lowers blood pressure. It is widely used in Europe but not approved in the US.
udenafil
A medication used to treat erectile dysfunction (ED). Like other drugs in its class, it works by increasing blood flow to the penis. It is approved in several countries, but not in the US.
unoprostone
An eye drop used to reduce high pressure inside the eye in people with open-angle glaucoma or ocular hypertension. It was discontinued in the US but remains available in other countries.
ulinastatin
An intravenous medication used to treat serious conditions like pancreatitis and sepsis by inhibiting enzymes that cause widespread inflammation. It is primarily used in Asian countries.
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