This list includes 50 Medications that start with E, from “Eculizumab” to “Ezetimibe”. It highlights widely used generic drugs spanning cholesterol control, autoimmune therapy, infection care and common symptom relief.

[Medications that start with E] are drugs whose names begin with “E” and treat a wide range of conditions. Notable examples include Ezetimibe for cholesterol and Eculizumab as a high-profile biologic.

Below you’ll find the table with [COLUMN_NAMES].

Generic name: The official nonproprietary name of the drug so you can identify the active substance quickly and accurately.

Brand names: Common trade names you may see on prescriptions or packaging to help you recognize marketed products.

Drug class: The therapeutic category that explains how the medication works and what other drugs it is related to.

Common uses: Typical conditions or symptoms treated so you can match each drug to likely clinical purposes.

Common side effects: Frequent, usually mild adverse effects to watch for so you know what reactions are most reported.

Typical dosage forms: The usual forms such as tablets, injections, or creams so you recognize how the medication is normally given.

Last updated: 2025-09-28

Medical disclaimer: This information is for general reference and does not replace professional medical advice.

Medications that start with E

Generic nameCommon brand namesDrug classCommon uses/indications
EnalaprilVasotec, EpanedACE inhibitorHigh blood pressure, heart failure
EscitalopramLexapro, CipralexSSRI antidepressantDepression, generalized anxiety disorder
EsomeprazoleNexium, EsotrexProton pump inhibitor (PPI)GERD, heartburn, stomach ulcers
EszopicloneLunestaZ-drug hypnoticInsomnia (trouble sleeping)
EzetimibeZetiaCholesterol absorption inhibitorHigh cholesterol
EpinephrineEpiPen, Adrenalin, Auvi-QAdrenergic agonistSevere allergic reactions (anaphylaxis)
ErythromycinEry-Tab, E.E.S., ErythrocinMacrolide antibioticBacterial infections
EtanerceptEnbrel, ErelziTNF inhibitorRheumatoid arthritis, psoriasis, ankylosing spondylitis
EtonogestrelNexplanon, NuvaRingProgestin contraceptiveBirth control (contraception)
EtodolacLodineNSAIDPain, arthritis
ExenatideByetta, BydureonGLP-1 receptor agonistType 2 diabetes
EfavirenzSustivaNNRTI antiretroviralHIV infection
EletriptanRelpaxTriptanMigraine headaches
EmtricitabineEmtrivaNRTI antiretroviralHIV infection, HIV prevention (PrEP)
EplerenoneInspraAldosterone antagonistHigh blood pressure, heart failure
Epoetin alfaEpogen, Procrit, RetacritErythropoiesis-stimulating agentAnemia
ErlotinibTarcevaTyrosine kinase inhibitorLung cancer, pancreatic cancer
EstradiolEstrace, Vivelle-Dot, EstringEstrogen hormoneMenopause symptoms, hormone therapy
EthambutolMyambutolAntitubercular agentTuberculosis (TB)
EthosuximideZarontinAnticonvulsantAbsence seizures
EtoposideToposar, VePesidTopoisomerase II inhibitorCancer (lung, testicular)
EverolimusAfinitor, ZortressmTOR inhibitorCancer, organ transplant rejection
ExemestaneAromasinAromatase inhibitorBreast cancer
EvolocumabRepathaPCSK9 inhibitorHigh cholesterol
EmpagliflozinJardianceSGLT2 inhibitorType 2 diabetes, heart failure
EdoxabanSavaysa, LixianaFactor Xa inhibitorBlood clot prevention and treatment
ElagolixOrilissaGnRH antagonistEndometriosis pain
ElexacaftorTrikafta (in combination)CFTR modulatorCystic fibrosis
EltrombopagPromacta, RevoladeTPO receptor agonistLow platelet counts (ITP)
EnzalutamideXtandiAndrogen receptor inhibitorProstate cancer
Estrogens, conjugatedPremarinEstrogen hormoneMenopause symptoms
Ethinyl estradiolLoestrin, Yaz, Yasmin (in combinations)Estrogen hormoneBirth control (contraception)
EculizumabSolirisMonoclonal antibody (C5 inhibitor)PNH, aHUS (rare blood disorders)
EdaravoneRadicavaFree radical scavengerAmyotrophic lateral sclerosis (ALS)
EfinaconazoleJubliaAzole antifungalToenail fungus
EptifibatideIntegrilinGlycoprotein IIb/IIIa inhibitorHeart attack, angioplasty
EsketamineSpravatoNMDA receptor antagonistTreatment-resistant depression
EravacyclineXeravaTetracycline antibioticComplicated intra-abdominal infections
Empagliflozin/MetforminSynjardySGLT2 inhibitor / biguanide combinationType 2 diabetes
EntrectinibRozlytrekTyrosine kinase inhibitorCancers with NTRK or ROS1 fusion
EncorafenibBraftoviBRAF kinase inhibitorMelanoma, colorectal cancer
Enfortumab vedotinPadcevAntibody-drug conjugateBladder cancer (urothelial)
ElvitegravirVitekta, Genvoya (in combination)INSTI antiretroviralHIV infection
EmicizumabHemlibraMonoclonal antibodyHemophilia A
EnasidenibIdhifaIDH2 inhibitorAcute myeloid leukemia (AML)
Eslicarbazepine acetateAptiomAnticonvulsantEpilepsy (partial-onset seizures)
EvinacumabEvkeezaANGPTL3 inhibitorHomozygous familial hypercholesterolemia
EtelcalcetideParsabivCalcimimeticSecondary hyperparathyroidism in dialysis
EluxadolineViberziOpioid receptor agonist/antagonistIrritable bowel syndrome with diarrhea (IBS-D)
EtravirineIntelenceNNRTI antiretroviralHIV infection

Descriptions

Enalapril
Relaxes blood vessels to lower blood pressure and improve heart function. Side effects can include a persistent dry cough, dizziness, and headache. It is important to monitor kidney function and potassium levels.
Escitalopram
Works by increasing levels of serotonin, a mood-regulating chemical in the brain. Common side effects include nausea, insomnia, and sexual dysfunction. It may take several weeks to feel the full effects.
Esomeprazole
Reduces the amount of acid your stomach produces, providing relief from acid-related conditions. Long-term use should be discussed with a doctor due to potential risks like bone fractures and nutrient deficiencies.
Eszopiclone
Helps you fall asleep faster and stay asleep longer. It can cause an unpleasant metallic taste, next-day drowsiness, and dizziness. This medication is intended for short-term use.
Ezetimibe
Lowers cholesterol by preventing its absorption from the food you eat. It is often prescribed along with a statin medication. Side effects may include diarrhea, joint pain, and fatigue.
Epinephrine
A life-saving emergency medicine used to treat anaphylaxis. It works quickly to open airways and tighten blood vessels. Side effects are temporary and include a racing heart, shakiness, and anxiety.
Erythromycin
Treats a wide range of bacterial infections, including those affecting the skin and respiratory tract. Stomach upset is a very common side effect. It is available as pills, liquids, and topical creams.
Etanercept
A biologic medication that reduces inflammation by blocking a substance called TNF. It is given by injection. It can increase the risk of serious infections, so careful monitoring is required.
Etonogestrel
A synthetic hormone used to prevent pregnancy. It is available as a small, long-acting implant placed in the arm (Nexplanon) or as part of a vaginal ring (NuvaRing).
Etodolac
A nonsteroidal anti-inflammatory drug that reduces pain, swelling, and stiffness from arthritis or injury. Long-term use can increase the risk of stomach ulcers and heart problems.
Exenatide
An injectable medication that helps control blood sugar by increasing insulin production and slowing digestion. Nausea is a common side effect, especially when starting the medication.
Efavirenz
Part of a combination therapy for treating HIV. It prevents the virus from making copies of itself. It is often taken at bedtime to minimize central nervous system side effects like dizziness and vivid dreams.
Eletriptan
Treats migraine attacks after they have started by narrowing blood vessels in the brain. It does not prevent migraines. Side effects can include dizziness, drowsiness, and a feeling of chest tightness.
Emtricitabine
A cornerstone medication used with other drugs to treat or prevent HIV. It’s a key component in many single-tablet regimens. Generally well-tolerated, with side effects like headache or nausea.
Eplerenone
A type of diuretic (water pill) that helps lower blood pressure and reduce strain on the heart, especially after a heart attack. It can raise potassium levels, so blood tests are necessary.
Epoetin alfa
A man-made protein that signals the body to produce more red blood cells. It is used to treat anemia caused by chronic kidney disease or chemotherapy. Given as an injection under the skin or into a vein.
Erlotinib
A targeted therapy drug that blocks signals that cause cancer cells to grow and divide. It is a daily pill. A skin rash is a very common side effect, often indicating the drug is working.
Estradiol
An estrogen hormone used to relieve symptoms of menopause, such as hot flashes and vaginal dryness. It is available in many forms, including pills, skin patches, gels, and creams.
Ethambutol
An antibiotic that is always used in combination with other drugs to treat active tuberculosis. It can cause vision problems, so regular eye exams are crucial during treatment.
Ethosuximide
A medication used specifically to control absence (or “petit mal”) seizures, a form of epilepsy. Common side effects include nausea, stomach pain, drowsiness, and hiccups.
Etoposide
A chemotherapy drug that interferes with cancer cell growth and division. It is given by IV or as an oral capsule. It commonly causes hair loss, low blood counts, and nausea.
Everolimus
Used to treat certain types of cancer (like kidney and breast) or to prevent the body from rejecting a transplanted organ. It can cause mouth sores, rash, and an increased risk of infection.
Exemestane
An oral medication used to treat hormone-receptor-positive breast cancer in women after menopause. It works by significantly lowering estrogen levels. Common side effects include hot flashes and joint pain.
Evolocumab
A powerful, injectable medication for lowering LDL (“bad”) cholesterol. It is used when statins are not enough or not tolerated. Injections are typically given every two to four weeks.
Empagliflozin
A daily pill that lowers blood sugar by forcing the kidneys to remove excess sugar through urine. It has proven benefits for protecting the heart and kidneys. Can increase the risk of yeast and urinary tract infections.
Edoxaban
An oral anticoagulant (blood thinner) used to prevent stroke in people with atrial fibrillation or to treat deep vein thrombosis (DVT). The main risk is an increased chance of bleeding.
Elagolix
An oral medication that manages moderate to severe pain from endometriosis by lowering estrogen levels. Side effects can include hot flashes, headaches, and nausea. Long-term use may affect bone density.
Elexacaftor
A key part of a breakthrough combination therapy that helps the defective protein in cystic fibrosis work more effectively for people with certain genetic mutations. It has significantly improved quality of life.
Eltrombopag
A medication that stimulates the bone marrow to produce more platelets, helping to prevent bleeding. It is used for conditions like chronic ITP and aplastic anemia. Requires regular blood monitoring.
Enzalutamide
An oral medication for advanced prostate cancer that works by blocking testosterone from fueling cancer cell growth. Common side effects include extreme tiredness, hot flashes, and back pain.
Estrogens, conjugated
A mixture of estrogen hormones, typically derived from natural sources, used to treat hot flashes and other symptoms of menopause. It is available as a pill, cream, or injection.
Ethinyl estradiol
A synthetic form of estrogen that is a primary component in nearly all combination birth control pills, patches, and rings. It works with a progestin to prevent ovulation.
Eculizumab
A highly specialized intravenous drug used to treat rare and life-threatening blood and kidney disorders. It increases the risk of serious meningococcal infections, so vaccination is required before starting.
Edaravone
An intravenous medication that may help slow the decline in physical function for people with ALS. Its mechanism is thought to involve reducing oxidative stress in the nervous system.
Efinaconazole
A topical liquid applied directly to the affected toenail once daily for up to 48 weeks. It is one of the more effective topical treatments for fungal nail infections, but requires consistent use.
Eptifibatide
A potent antiplatelet drug given intravenously in a hospital to prevent blood clots during a heart attack or a cardiac procedure like stenting. Its main side effect is bleeding.
Esketamine
A prescription nasal spray used for adults with depression that has not responded to other treatments. It must be administered in a certified healthcare setting due to potential side effects like dissociation and sedation.
Eravacycline
A powerful intravenous antibiotic used to treat serious bacterial infections inside the abdomen. It was designed to work against bacteria that have become resistant to other antibiotics.
Empagliflozin/Metformin
A combination pill containing two medications that work in different ways to lower blood sugar in people with type 2 diabetes. It is a convenient option to reduce the number of pills taken daily.
Entrectinib
A targeted cancer therapy for solid tumors that have a specific genetic abnormality (NTRK or ROS1 fusion), regardless of where in the body the cancer started. It can cause fatigue, constipation, and dizziness.
Encorafenib
A targeted therapy pill used in combination with other drugs to treat cancers that have a specific BRAF gene mutation. It blocks the signals that help cancer cells grow.
Enfortumab vedotin
A targeted therapy that acts like a guided missile, delivering a powerful chemotherapy agent directly to cancer cells that have a specific protein on their surface. Given by IV infusion.
Elvitegravir
An integrase inhibitor medication for HIV that blocks the virus’s ability to insert its DNA into the host cell’s DNA, preventing replication. It is typically found in single-tablet, combination regimens.
Emicizumab
A preventative treatment given by injection under the skin to reduce the frequency of bleeding episodes in people with hemophilia A. It works by mimicking the function of a missing clotting factor.
Enasidenib
A targeted oral therapy for adults with relapsed AML that has a specific IDH2 gene mutation. It works by blocking an enzyme that promotes cancer cell growth.
Eslicarbazepine acetate
A once-daily medication used to control partial-onset seizures in adults and children. It is chemically related to carbamazepine and oxcarbazepine but may have fewer side effects for some people.
Evinacumab
An intravenous medication for a rare, severe genetic form of high cholesterol. It is used in addition to other cholesterol-lowering treatments to dramatically reduce LDL levels.
Etelcalcetide
An intravenous medication administered during hemodialysis to control overactive parathyroid glands. It helps lower high levels of parathyroid hormone (PTH), calcium, and phosphorus in the blood.
Eluxadoline
An oral medication that works on opioid receptors in the gut to reduce abdominal pain and diarrhea associated with IBS-D. It is a controlled substance due to a potential for dependence.
Etravirine
An antiretroviral medication used to treat HIV in patients who have developed resistance to other drugs in the same class. It is taken twice daily with a meal. Rash is a common side effect.
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