This list includes 60 Hard words that start with L, from “labefaction” to “lysosome”. They are mostly low-frequency, polysyllabic, and cross-disciplinary words useful in study, writing, editing, and wordplay.

Hard words that start with L are challenging, often obscure or technical vocabulary items that expand your precision and comprehension. Many have interesting histories, and some, like “lysosome”, entered popular science and testing vocabularies.

Below you’ll find the table with the word, concise etymology, and a one-sentence definition.

Word: The headword shown in quotes so you can spot and locate each entry quickly.

Etymology: The word’s origin and root elements, helping you understand history and related words.

Definition: A concise part-of-speech and one-sentence meaning you can use for study or quick reference.

Hard words that start with L

Word Part of speech Etymology Syllables Description
labefaction noun Latin labefactare ’cause to fall’, 17th c. 4 noun. weakening or moral/political decay, used in historical, rhetorical, or critical discussion.
labile adj. Latin labilis ‘slipping’, 19th c. 2 adj. chemically or psychologically unstable or prone to change, used in science and clinical contexts.
lacuna noun Latin lacuna ‘pit, gap’, c.1600 3 noun. a gap or missing portion in a manuscript, argument, or record; common in scholarship.
lacustrine adj. Latin lacus ‘lake’ + -ine, 19th c. 3 adj. relating to lakes or lake deposits, used in geology, ecology, and sedimentology.
lachrymose adj. Latin lacrima ‘tear’, 17th c. 3 adj. tearful or sorrowful; a literary word for melancholic tone or expression.
laciniate adj. Latin lacinia ‘fringe, flap’, 17th c. 4 adj. cut into deep lobes or fringed segments, used in botany and anatomy.
lacrymatory noun Latin lacrima ‘tear’ + -ory, c.1600 5 noun. a small ancient vessel supposedly used to collect tears; term appears in archaeology.
lallation noun Latin lallare ‘to babble’, 18th c. 4 noun. infantile babbling or a speech defect; used in phonetics and pathology descriptions.
lamella noun Latin lamella ‘thin plate’, Medieval Latin 3 noun. a thin plate or membrane in biology, materials science, or anatomy.
laminar adj. Latin lamina ‘thin plate’, 19th c. 3 adj. describing smooth, layered flow in fluids or layered structural forms.
laminitis noun Latin lamina + -itis, 19th c. 4 noun. painful inflammation of the hoof in horses, used in veterinary medicine.
lamprophyre noun Greek lampros ‘bright’ + pyros ‘fire’, 19th c. 4 noun. a dark, potassium-rich igneous rock, term used in geology and petrology.
lancinate adj. Latin lancinatus ‘lacerated’, 17th c. 3 adj. furnished with long narrow lobes or pointed projections; used in botanical description.
laryngectomy noun Greek larynx + -ectomy, 19th c. 5 noun. surgical removal of the larynx, a term in medicine and surgical oncology.
laryngology noun Greek larynx + -logy, 19th c. 5 noun. the medical specialty studying the larynx and related disorders.
laryngitis noun Greek larynx + -itis, classical/19th c. 4 noun. inflammation of the larynx, producing hoarseness or voice loss; common clinical diagnosis.
lascivious adj. Latin lascivus ‘wanton’, 16th c. 4 adj. overtly sexual or lewd; often used in legal, moral, or literary contexts.
lassitude noun Latin lassitudo ‘weariness’, 16th c. 3 noun. a state of physical or mental weariness; used in literary or medical descriptions.
latifundium noun Latin latus ‘broad’ + fundus ‘farm’, classical 5 noun. a large landed estate, especially in ancient Rome or agrarian history.
latitudinarian adj. Latin latitudo ‘breadth’ + -arian, 17th c. 7 adj. favoring broad tolerance or doctrinal flexibility, often used in religious or political history.
legerdemain noun French léger de main ‘light of hand’, 18th c. 4 noun. sleight of hand or deceptive skill, used for magic or cunning maneuvering.
lethologica noun Greek lethe ‘forgetfulness’ + -logia, 19th c. 5 noun. the temporary inability to recall a familiar word; noted in psychology and linguistics.
lethargy noun Greek lethargos ‘forgetful, drowsy’, c.1600 3 noun. extreme tiredness or sluggishness; used in clinical, literary, and everyday contexts.
leucocyte noun Greek leukos ‘white’ + kytos ‘cell’, 19th c. 3 noun. a white blood cell involved in immune response; medical and biological term.
leucistic adj. Greek leukos ‘white’ + -istic, 19th c. 3 adj. describing reduced pigmentation in animals, used in biology and zoology.
leucine noun Greek leukos ‘white’, 19th c. 2 noun. an essential amino acid in proteins, term used in biochemistry and nutrition.
lepidopterist noun Greek lepidos ‘scale’ + pteron ‘wing’, 19th c. 5 noun. a scientist or hobbyist who studies or collects butterflies and moths.
leporine adj. Latin lepus ‘hare’, Latin-derived 3 adj. relating to hares or resembling a hare; used in zoological descriptions.
lexiphanic adj. Greek lexis ‘word’ + phainein ‘show’, 18th c. 4 adj. pompous or pretentious in diction; a critical literary adjective.
lexeme noun Greek lex- ‘word’, modern linguistics 2 noun. the minimal unit of meaning in linguistic analysis; used in lexicography and linguistics.
libidinal adj. Latin libido ‘desire’ + -al, 19th c. 4 adj. relating to sexual drive or psychic energy, used in psychology and psychoanalysis.
ligneous adj. Latin lignum ‘wood’, Medieval Latin 3 adj. woody or resembling wood, used in botany and anatomy.
lignify verb Latin lignum ‘wood’ + -fy, 18th c. 3 verb. to turn into wood or to become woody; used in botany and material science.
liminal adj. Latin limen ‘threshold’, 20th c. 3 adj. relating to thresholds or transitional states, common in anthropology and psychology.
liminality noun Latin limen ‘threshold’, 20th c. 5 noun. the quality of being on a threshold or in-between state; used in cultural studies.
limnology noun Greek limne ‘lake’ + -logy, 19th c. 4 noun. scientific study of inland waters, lakes, and freshwater ecosystems.
limnetic adj. Greek limne ‘lake’, ecology usage, 19th c. 3 adj. pertaining to open freshwater zones, used in limnology and ecology.
lineament noun Latin linea ‘line’, 16th c. 4 noun. a distinctive linear feature of landscape or face; used in geology and physiognomy.
litotes noun Greek litos ‘plain’, classical/17th c. 3 noun. a rhetorical understatement using double negatives, common in literary analysis.
lobate adj. Latin lobus ‘lobe’, 17th c. 2 adj. having lobes or rounded projections; used in botany, anatomy, and morphology.
lobotomy noun Greek lobos ‘lobe’ + -otomy, 20th c. 4 noun. surgical severing of brain tissue historically used in psychiatry; now largely obsolete.
logomachy noun Greek logos ‘word’ + machē ‘battle’, 17th c. 4 noun. an argument about words or meanings; literary and philosophical term.
logorrhea noun Greek logos ‘word’ + rheō ‘flow’, 19th c. 4 noun. excessive, often incoherent talkativeness; used in psychology and criticism.
logophile noun Greek logos ‘word’ + philos ‘lover’, 19th c. 3 noun. a lover of words or vocabulary enthusiast; informal scholarly term.
louche adj. French louche ‘shady, dubious’, 19th c. 1 adj. disreputable or of questionable taste; used in literary and social description.
lugubrious adj. Latin lugubris ‘mournful’, 17th c. 4 adj. excessively mournful or gloomy; a literary adjective for tone or demeanor.
lumbago noun Latin lumbus ‘loin’, 18th c. 3 noun. lower back pain or sciatica-like discomfort; used in medical and lay contexts.
luminescence noun Latin lumen ‘light’ + -escence, 19th c. 4 noun. emission of light not caused by heat, used in physics and materials science.
lumen noun Latin lumen ‘light’, classical 2 noun. a measure of light or the interior cavity of a vessel; used in physics and anatomy.
lustration noun Latin lustratio ‘purification ritual’, classical 3 noun. ritual purification or political cleansing process, used in anthropology and politics.
lustrum noun Latin lustrum ‘five-year period’, classical 2 noun. a five-year span; used in historical and classical contexts.
luxation noun Latin luxatio ‘dislocation’, 17th c. 3 noun. displacement of a bone from its joint; medical term for dislocation.
lycanthropy noun Greek lykos ‘wolf’ + anthropos ‘man’, medieval 4 noun. the mythical or delusional condition of becoming a wolf; used in folklore and psychiatry.
lyophilization noun Greek lyo ‘dissolve’ + phile ‘loving’ + -ization, 20th c. 6 noun. freeze-drying process used in pharmaceuticals and food preservation.
lymphocyte noun Greek lympha ‘lymph’ + kytos ‘cell’, 19th c. 3 noun. a type of white blood cell critical to immune response; immunology term.
lymphatic adj. Greek lympha ‘lymph’, medical usage, 18th c. 3 adj. relating to the lymphatic system; used in anatomy and medicine.
lysosome noun Greek lys- ‘break down’ + -some, 20th c. 3 noun. cell organelle containing enzymes for digestion; core term in cell biology.
lysis noun Greek lysis ‘loosening, dissolution’, 19th c. 2 noun. the disintegration or destruction of cells, used in biology and medicine.
lyase noun Greek lyo ‘loosen’ + -ase, 20th c. 2 noun. an enzyme class catalyzing bond cleavage without hydrolysis; biochemical term.
lexicography noun Greek lexis ‘word’ + -graphy, 19th c. 5 noun. the practice of compiling dictionaries and describing word usage; academic linguistic field.

Descriptions

labefaction
labile
lacuna
lacustrine
lachrymose
laciniate
lacrymatory
lallation
lamella
laminar
laminitis
lamprophyre
lancinate
laryngectomy
laryngology
laryngitis
lascivious
lassitude
latifundium
latitudinarian
legerdemain
lethologica
lethargy
leucocyte
leucistic
leucine
lepidopterist
leporine
lexiphanic
lexeme
libidinal
ligneous
lignify
liminal
liminality
limnology
limnetic
lineament
litotes
lobate
lobotomy
logomachy
logorrhea
logophile
louche
lugubrious
lumbago
luminescence
lumen
lustration
lustrum
luxation
lycanthropy
lyophilization
lymphocyte
lymphatic
lysosome
lysis
lyase
lexicography
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